Partial Enteral Nutrition combined with regular diet has not been considered to be effective for inducing remission (Lee D et al). However, it’s current use in combination with anti-inflammatory diets is showing great promise as an effective alternative to induce remission (Sigall-Boneh R et al) (Levine A et al) (Urlep D et al). For maintenance therapy, patients receiving PEN even with regular diet have shown a higher rate of maintaining clinical remission at one year than those not receiving nutritional therapy (Yang H et al). A new clinical trial, BIOPIC (BIOlogics and Partial enteral nutrition), in adults with active ileocolonic Crohn’s disease is evaluating the use of PEN given as fifty percent of calories in combination with biologics. Partial enteral nutrition in combination with diet or medications is a promising nutritional option to help maintain remission.

PEN Research

Published Research

View the published research for PEN, including highlighted featured research followed by the complete list.

Research Summaries

View published review articles summarizing the existing research to date on nutritional therapy.

Ongoing Trials

View a list of the ongoing clinical trials studying PEN.

PEN Clinician Resources

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PEN Patient Resources

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Nutritional Therapy for IBD

Improving the Care of Patients with Crohn’s Disease and Ulcerative Colitis through Nutrition

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