A Mediterranean Diet Pattern Improves Intestinal Inflammation Concomitant with Reshaping of the Bacteriome in Ulcerative Colitis: A Randomised Controlled Trial
MED
An MDP induces gut microbiome alterations associated with the maintenance of clinical remission and reduced FC in patients with quiescent UC. The data support that the MDP is a sustainable diet pattern that could be recommended as a maintenance diet and adjunctive therapy for UC patients in clinical remission.
Journal of Crohn's and Colitis, 2023;, jjad073, https://doi.org/10.1093/ecco-jcc/jjad073
Authors: Haskey N. et al.
A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults with Crohn's Disease
SCD,
MED
This study compares the SCD and MD on symptoms, fecal calprotectin and CRP at 6 and 12 weeks finding no statistical significance in these endpoints.
Gastroenterology. 2021;S0016-5085(21)03069-9. doi:10.1053/j.gastro.2021.05.047
Authors: Lewis JD et al
Adherence to the Mediterranean Diet Improved Clinical Scores and Inflammatory Markers in Children with Active Inflammatory Bowel Disease: A Randomized Trial
MED
Adherence to the Mediterranean diet improves clinical scores and inflammatory markers in children and adolescents with mild-moderate active IBD.
J Inflamm Res. 2022;15:2075-2086. doi:10.2147/JIR.S349502
Authors: El Amrousy D, et al.
Adherence to the Mediterranean Diet Is Associated with Decreased Fecal Calprotectin in Patients with Ulcerative Colitis after Pouch Surgery
MED
In patients with UC after pouch surgery, adherence to MED is associated with decreased calprotectin levels. Thus, MED may have a role in modifying intestinal inflammation in IBD.
Eur J Nutr . 2020 Oct;59(7):3183-3190. doi: 10.1007/s00394-019-02158-3. Epub 2019 Dec 7.
Authors: Godny L et al
An Anti-Inflammatory Diet as Treatment for Inflammatory Bowel Disease: a Case Series Report
IBD-AID
This case series indicates potential for the IBD-AID as an adjunct dietary therapy for the treatment of IBD. A randomized clinical trial is warranted.
Nutr J. 2014 Jan 16;13:5. doi: 10.1186/1475-2891-13-5
Authors: Olendzki B et al
An Autoimmune Protocol Diet Improves Patient-Reported Quality of Life in Inflammatory Bowel Disease
AIP
Dietary modification can improve quality of life as early as week 3 in patients with active IBD. Larger randomized controlled trials are needed to examine dietary interventions in IBD.
Crohn's & Colitis 360, Volume 1, Issue 3, October 2019, otz019,
Authors: Chandrasekaran A et al
Analysis of Gut Microbiome and Diet Modification in Patients with Crohn's Disease
SCD
Changes in the composition and complexity of the gut microbiome were identified in response to specialized carbohydrate diet. The SCD was associated with restructuring of the gut microbial communities.
SOJ Microbiol Infect Dis. 2014;2(3):1-13. doi: 10.15226/sojmid/2/3/00122. Epub 2014 Jun 27.
Authors: Walters SS et al
Assessing Barriers to use of the Specific Carbohydrate Diet in Pediatric Inflammatory Bowel Disease: A Qualitative Study
SCD
To our knowledge, this is the first study examining barriers to the SCD among pediatric IBD patients.
JPGN Reports. 2022;3(3):e239
Authors: Schwartz N., et al.
Clinical Course and Dietary Patterns Among Patients Incorporating the Autoimmune Protocol for Management of Inflammatory Bowel Disease
AIP
Patients utilizing AIP for management of IBD report clinical benefit of AIP, reduction of steroid use, and successful food group reintroduction. Dietary interventions could be another form of treatment in patients with IBD to improve symptoms and maintain remission.
Current Developments in Nutrition, Volume 3, Issue Supplement_1, June 2019, nzz035.P12-010-19
Authors: Lee J et al
Clinical and Fecal Microbial Changes With Diet Therapy in Active Inflammatory Bowel Disease
SCD
SCD therapy in IBD is associated with clinical and laboratory improvements as well as concomitant changes in the fecal microbiome. Further prospective studies are required to fully assess the safety and efficacy of dietary therapy in patients with IBD.
J Clin Gastroenterol. 2018 Feb;52(2):155-163. doi: 10.1097/MCG.0000000000000772.
Authors: Suskind DL et al
Photo Credit: Adisa/Shutterstock
Clinical and Histologic Remission in an Adult Crohn’s Disease Patient Following the Specific Carbohydrate Diet and Its Impact on Healthcare Costs
SCD
This case highlights the rapid and sustainable benefits of the SCD intervention in Crohn’s disease from both a clinical and economic standpoint.
Cureus 14(2): e22032. doi:10.7759/cureus.22032
Authors: Arjomand, A
Clinical and Mucosal Improvement with Specific Carbohydrate Diet in Pediatric Crohn Disease
SCD
Clinical and mucosal improvements were seen in children with CD, who used SCD for 12 and 52 weeks. In addition, CE can monitor mucosal improvement in treatment trials for pediatric CD. Further studies are critically needed to understand the mechanisms underlying SCD's effectiveness in children with CD.
J Pediatr Gastroenterol Nutr. 2014 Oct;59(4):516-21. doi: 10.1097/MPG.0000000000000449.
Authors: Cohen SA et al
