Nutritional Therapy Research

Featured Research

Successful Dietary Therapy in Paediatric Crohn's Disease is Associated with Shifts in Bacterial Dysbiosis and Inflammatory Metabotype Towards Healthy Controls (CDED)

NTforIBD Comment: October 2022 Newsletter

Summary Excerpt: Successful dietary therapy induced correction of both compositional and functional dysbiosis. However, 12 weeks of diet was not enough to achieve complete correction of dysbiosis.

J Crohns Colitis. Published online September 15, 2022. doi: https://doi.org/10.1093/ecco-jcc/jjac105
Verburgt CM, et al.

Effect of the Crohn’s Disease Exclusion Diet (CDED) on the Fecal Calprotectin Level in Children with Active Crohn’s Disease (CDED)

NTforIBD Comment: October 2022 Newsletter

Summary Excerpt: In their conclusion, the authors wrote: “In the group under analysis, this nutritional intervention resulted in a significant decrease in FCP level and contributed to normalization of this parameter in one-third of patients, which is a similar or better result compared to pharmacological treatment.”

J Clin Med. 2022;11(14):4146. doi: https://doi.org/10.3390/jcm11144146
Matuszczyk M, et al.

Assessing Barriers to use of the Specific Carbohydrate Diet in Pediatric Inflammatory Bowel Disease: A Qualitative Study (SCD)

NTforIBD Comment: October 2022 Newsletter

Summary Excerpt: To our knowledge, this is the first study examining barriers to the SCD among pediatric IBD patients.

JPGN Reports. 2022;3(3):e239
Schwartz N., et al.

Perspectives on Specific Carbohydrate Diet Education from Inflammatory Bowel Disease Patients and Caregivers: A Needs Assessment (SCD)

NTforIBD Comment: October 2022 Newsletter

Summary Excerpt: Increasing educational content on the SCD to individuals, caregivers, and medical providers has the potential to improve adherence and sustainability on the SCD.

JPGN Reports. 2022;3(3):e222. doi: https://doi.org/10.1097/PG9.0000000000000222
Rivera, N. et al

Date Title Diets Authors Summary Excerpt Citation
Nov 2021 The Crohn's disease exclusion diet for induction and maintenance of remission in adults with mild-to-moderate Crohn's disease (CDED-AD): an open-label, pilot, randomised trial CDED Yanai, H. et al. CDED with or without partial enteral nutrition was effective for induction and maintenance of remission in adults with mild-to-moderate biologic naive Crohn's disease and might lead to endoscopic remission. Lancet Gastroenterol Hepatol. 2021;S2468-1253(21)00299-5. doi:10.1016/S2468-1253(21)00299-5
Dec 2020 The Specific Carbohydrate Diet and Diet Modification as Induction Therapy for Pediatric Crohn's Disease: A Randomized Diet Controlled Trial SCD, mSCD Suskind DL et al This study emphasizes the impact of diet in CD. Each diet had a positive effect on symptoms and inflammatory burden; the more exclusionary diets were associated with a better resolution of inflammation. Nutrients . 2020 Dec 6;12(12):E3749. doi: 10.3390/nu12123749
Aug 2015 The Specific Carbohydrate Diet for Inflammatory Bowel Disease: A Case Series SCD Kakodkar S et al Our survey results suggest that SCD can potentially be an effective tool in the management of some patients with IBD and specifically in patients with colonic and ileocolonic CD who made up the majority of our study group. A highly educated group of patients follow the SCD; all but one of the adults in our study had a college or graduate degree. Our results also suggest that in some patients with moderate to severe disease who follow this diet, discontinuation of immunosuppressive agents has been feasible. J Acad Nutr Diet. 2015 Aug;115(8):1226-32. doi: 10.1016/j.jand.2015.04.016
Apr 2019 Treatment of Active Crohn's Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition CD-TREAT Svolos V et al CD-TREAT replicates EEN changes in the microbiome, decreases gut inflammation, is well tolerated, and is potentially effective in patients with active CD. Gastroenterology . 2019 Apr;156(5):1354-1367.e6. doi: 10.1053/j.gastro.2018.12.002. Epub 2018 Dec 11.

Nutritional Therapy for IBD

Improving the Care of Patients with Crohn’s Disease and Ulcerative Colitis through Nutrition


Like what you see here?

Your donations will help us to improve the outcomes of patients with IBD through nutrition.