An Anti-Inflammatory Diet as Treatment for Inflammatory Bowel Disease: a Case Series Report
IBD-AID
This case series indicates potential for the IBD-AID as an adjunct dietary therapy for the treatment of IBD. A randomized clinical trial is warranted.
Nutr J. 2014 Jan 16;13:5. doi: 10.1186/1475-2891-13-5
Authors: Olendzki B et al
Perspectives on Specific Carbohydrate Diet Education from Inflammatory Bowel Disease Patients and Caregivers: A Needs Assessment
SCD
Increasing educational content on the SCD to individuals, caregivers, and medical providers has the potential to improve adherence and sustainability on the SCD.
JPGN Reports. 2022;3(3):e222. doi: https://doi.org/10.1097/PG9.0000000000000222
Authors: Rivera, N. et al
Randomised Clinical Trial: Exclusive Enteral Nutrition Versus Standard of Care for Acute Severe Ulcerative Colitis
EEN
Patients on EEN had a shorter hospital stay [median (range) 10 (8-17) vs 13 (8-24) days; P = 0.04], higher day 7 albumin level (34 ± 4 vs 29 ± 3 g/L, P < 0.01), greater reduction in serum C-reactive protein and faecal calprotectin levels (both P = 0.04) and a lower composite outcome of colectomy/hospitalisation at 6 months (16% vs 39%; P = 0.045) compared to SOC.
Aliment Pharmacol Ther . 2021 Jan 13. doi: 10.1111/apt.16249
Authors: Sahu P et al
Assessing Barriers to use of the Specific Carbohydrate Diet in Pediatric Inflammatory Bowel Disease: A Qualitative Study
SCD
To our knowledge, this is the first study examining barriers to the SCD among pediatric IBD patients.
JPGN Reports. 2022;3(3):e239
Authors: Schwartz N., et al.
Elemental Diet Therapy Plays a Significant Role in Preventing Surgical Recurrence of Crohn's Disease in the Era of Biologics
PEN
Although univariate analyses revealed that all three treatment strategies had significant effects on surgical recurrence in patients with CD, multivariate analysis revealed that only ED therapy was significantly associated with surgical recurrence rates. Thus, ED therapy plays an important role in the management of CD, even in the era of biological therapies.
Surg Today . 2021 Feb;51(2):250-257. doi: 10.1007/s00595-020-02112-5. Epub 2020 Aug 18.
Authors: Shinozaki M et al
Dietary Therapies Induce Rapid Response and Remission in Pediatric Patients With Active Crohn's Disease
CDED,
EEN
For pediatric patients with active CD, dietary therapies (CDED and EEN) induce a rapid clinical response (by week 3). Identification of patients with and without a rapid response to diet might help identify those who, with compliance, will be in clinical remission by week 6 of the diet.
Clin Gastroenterol Hepatol . 2020 Apr 14;S1542-3565(20)30487-0. doi: 10.1016/j.cgh.2020.04.006.
Authors: Sigall Boneh R et al
Partial Enteral Nutrition With a Crohn's Disease Exclusion Diet Is Effective for Induction of Remission in Children and Young Adults With Crohn's Disease
CDED,
PEN
Dietary therapy involving PEN with an exclusion diet seems to lead to high remission rates in early mild-to-moderate luminal Crohn's disease in children and young adults.
Inflamm Bowel Dis , 20 (8), 1353-60 Aug 2014
Authors: Sigall-Boneh R et al
Dietary Therapy With the Crohn's Disease Exclusion Diet Is a Successful Strategy for Induction of Remission in Children and Adults Failing Biological Therapy
CDED
Dietary treatment combining PEN with the CDED may be a useful salvage regimen for patients failing biological therapy despite dose escalation.
J Crohns Colitis , 11 (10), 1205-1212 2017 Oct 1
Authors: Sigall-Boneh RS et al
Effectiveness of Mediterranean Diet's Adherence in children with Inflammatory Bowel Diseases
MED
Children with IBD in remission have a sub-optimal food intake compared to HCs. MD seems to correlate to decreased intestinal inflammation.
Nutrients . 2020 Oct 20;12(10):3206. doi: 10.3390/nu12103206.
Authors: Strisciuglio C et al
The Specific Carbohydrate Diet and Diet Modification as Induction Therapy for Pediatric Crohn's Disease: A Randomized Diet Controlled Trial
SCD,
mSCD
This study emphasizes the impact of diet in CD. Each diet had a positive effect on symptoms and inflammatory burden; the more exclusionary diets were associated with a better resolution of inflammation.
Nutrients . 2020 Dec 6;12(12):E3749. doi: 10.3390/nu12123749
Authors: Suskind DL et al
Nutritional Therapy in Pediatric Crohn Disease: the Specific Carbohydrate Diet.
SCD
This chart review suggests that the SCD and other low complex carbohydrate diets may be possible therapeutic options for pediatric Crohn disease. Further prospective studies are required to fully assess the safety and efficacy of the SCD, or any other low complex SCDs in pediatric patients with Crohn disease.
J Pediatr Gastroenterol Nutr. 2014 Jan;58(1):87-91. doi: 10.1097/MPG.0000000000000103.
Authors: Suskind DL et al
Patients Perceive Clinical Benefit with the Specific Carbohydrate Diet for Inflammatory Bowel Disease
SCD
Individuals perceived clinical improvement on the SCD. Four percent reported clinical remission prior to the SCD, while 33 % reported remission at 2 months after initiation of the SCD, and 42 % at both 6 and 12 months. For those reporting clinical remission, 13 % reported time to achieve remission of less than 2 weeks, 17 % reported 2 weeks to a month, 36 % reported 1-3 months, and 34 % reported greater than 3 months. For individuals who reported reaching remission, 47 % of individuals reported associated improvement in abnormal laboratory values.
Dig Dis Sci. 2016 Nov;61(11):3255-3260. Epub 2016 Sep 16
Authors: Suskind DL et al