Publications Table

Date Title Diets Authors Summary Excerpt Citation
Apr 2019 An Overview of the Role of Exclusive Enteral Nutrition for Complicated Crohn's Disease EEN Adamji M and Day AS Published literature focusing upon the use of nutritional therapy as part of medical therapy in the management of complicated CD were identified and reviewed. Although there continue to be various interventions utilized for complicated CD, the currently available literature demonstrates that nutritional therapies, especially EEN, have important roles in the management of these complex scenarios. Intest Res. 2019 Apr; 17(2): 171–176.
Aug 2017 Diet, Gut Microbiome and Epigenetics: Emerging Links with Inflammatory Bowel Diseases and Prospects for Management and Prevention SCD, MD Aleksandrova K et al Other nutritional interventions or specific diets including the Specific Carbohydrate Diet (SCD), the low fermentable oligosaccharides, disaccharides, monosaccharides, and polyol (FODMAP) diet and, most recently, the Mediterranean diet have shown strong anti-inflammatory properties and show promise for improving disease symptoms. More work is required to evaluate the role of individual food compounds and complex nutritional interventions with the potential to decrease inflammation as a means of prevention and management of IBD. Nutrients. 2017 Aug 30;9(9). pii: E962. doi: 10.3390/nu9090962
Mar 2017 Potential Impact of Diet on Treatment Effect from Anti-TNF Drugs in Inflammatory Bowel Disease EEN Andersen V et al One small prospective study on diet and anti-TNF treatment in 56 patients with CD found similar remission rates after 56 weeks among 32 patients with good compliance that received concomitant enteral nutrition and 24 with poor compliance that had no dietary restrictions (78% versus 67%, p = 0.51). A meta-analysis of 295 patients found higher odds of achieving clinical remission and remaining in clinical remission among patients on combination therapy with specialised enteral nutrition and Infliximab (IFX) compared with IFX monotherapy (OR 2.73; 95% CI: 1.73-4.31, p < 0.01, OR 2.93; 95% CI: 1.66-5.17, p < 0.01, respectively) Nutrients , 9 (3) 2017 Mar 15
Jun 2015 Exclusive Enteral Nutrition in Children with Crohn’s Disease EEN Day AS and Lopez RN Exclusive enteral nutrition involves the use of a complete liquid diet, with the exclusion of normal dietary components for a defined period of time, as a therapeutic measure to induce remission in active Crohn's disease (CD). This very efficacious approach leads to high rates of remission, especially in children and adolescents newly diagnosed with CD. This intervention also results in mucosal healing, nutritional improvements and enhanced bone health. World J Gastroenterol , 21 (22), 6809-16 2015 Jun 14
Apr 2019 A Review of Dietary Therapy for IBD and a Vision for the Future EEN, SCD, IBD-AID, CDED, SVD, CD-TREAT Green N et al Dietary interventions, with known ability to modulate the intestinal microbiome, are a unique opportunity to improve outcomes in IBD. Dietary intervention trials are challenging, and capturing both broad dietary patterns as well as exposure to individual food compounds is important. With increasing patient interest and preliminary research in dietary therapy indicating efficacy, it is imperative to further advance the science of utilizing diet in IBD, as well as to support patients by proactively addressing diet within their care plan. Nutrients , 11 (5) 2019 Apr 26
Apr 2018 Enteral Nutrition in the Management of Pediatric and Adult Crohn's Disease EEN Hansen T and Duerksen DR In adults, EEN appears to be moderately beneficial for the induction of remission of CD; however, its use is understudied and underutilized. Stronger evidence is in place to support the use of EEN in pediatric CD with the added benefit of nutrition support and steroid-sparing therapy during the growth phase. Overall, EEN is an established therapy in inducing CD remission in the pediatric population while its role as primary therapy of adult Crohn's disease remains to be defined. Nutrients , 10 (5) 2018 Apr 26
Jun 2017 Specific Carbohydrate Diet for Inflammatory Bowel Disease — Learn About the SCD to Support Clients With IBD and How It Compares With Other Evidence-Based Nutritional Therapies SCD, EEN, PEN, IBD-AID Harris C Based on studies done thus far, the SCD appears to be an effective way to both establish and maintain remission for people with UC or CD. Both prospective and retrospective studies at different institutions with slightly different protocols have demonstrated benefits, and improvements have been observed in people of different ages and genders and with different locations and disease severity. Variants on the SCD, such as IBD-AID or "SCD-like" diets also may prove to be viable strategies—in fact, Seattle Children's Hospital is investigating the effectiveness of the SCD compared with a modified SCD with added foods, such as rice and oats, vs a more whole-foods based diet to see which strategy yields the best clinical results. Today's Dietitian Vol. 19, No. 6, P. 42
Nov 2019 Dietary Management of Pediatric Inflammatory Bowel Disease EEN, SCD, IBD-AID, CDED Kaenkumchorn T and Kesavan A In particular, nutritional therapies for IBD have garnered significant interest due to their limited side effect profile, bowel-sparing nature, and naturalistic approach. This review will examine the role of diet in the pathogenesis and malnutrition in IBD, and will discuss dietary approaches to management of IBD, including exclusive enteral nutrition, specific carbohydrate diet, anti-inflammatory diet, and food supplements (specifically curcumin and long-chain n-3 polyunsaturated fatty acids). J Med Food. 2019 Nov;22(11):1092-1099. doi: 10.1089/jmf.2019.0063. Epub 2019 Jul 18.
Dec 2017 Diet as a Therapeutic Option for Adult Inflammatory Bowel Disease SCD, EEN Kakodkar S and Mutlu EA The literature on diet and IBD is reviewed with a particular focus on EEN, SCD, and low FODMAP diets. Lessons learned from the existing observations and strengths and shortcomings of existing data are presented. Gastroenterol Clin North Am. 2017 Dec;46(4):745-767. doi: 10.1016/j.gtc.2017.08.016
Oct 2019 Importance of Nutritional Therapy in the Management of Intestinal Diseases: Beyond Energy and Nutrient Supply EEN Kim SE In this article, we review various dietary nutrients and their contribution to the pathogenesis and treatment of various intestinal diseases including inflammatory bowel disease, irritable bowel syndrome, colorectal cancer, and diverticulitis, among other such disorders. A better understanding of diet-host-gut microbiome interactions is essential to provide beneficial nutrients for gut health and to limit nutritional hazards to ensure successful nutritional management of gastrointestinal conditions in clinical practice. Intest Res , 17 (4), 443-454 Oct 2019
Aug 2015 Diet and Inflammatory Bowel Disease SCD, IBD-AID Knight-Sepulveda K et al The role of diet has become very important in the prevention and treatment of IBD. Although there is a general lack of rigorous scientific evidence that demonstrates which diet is best for certain patients, several diets-such as the low-fermentable oligosaccharide, disaccharide, monosaccharide, and polyol diet; the specific carbohydrate diet; the anti-inflammatory diet; and the Paleolithic diet-have become popular. This article discusses the diets commonly recommended to IBD patients and reviews the supporting data. Gastroenterol Hepatol (N Y). 2015 Aug;11(8):511-20.
Dec 2017 Dietary Therapies in Pediatric Inflammatory Bowel Disease: An Evolving Inflammatory Bowel Disease Paradigm EEN, PEN, SCD, CDED, IBD-AID Lane ER et al Recently, there has been growing interest and study of dietary interventions for induction and maintenance of remission. In addition to exclusive enteral nutrition, successes have been achieved with specific exclusion diets. This article evaluates current literature regarding the role of diet and nutrition in pathogenesis of disease, as well as the role of diet as primary therapy for pediatric IBD. Gastroenterol Clin North Am , 46 (4), 731-744 Dec 2017