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Date Title Categories Authors Summary Excerpt Citation
Mar 2017 Diet and Microbiota in Inflammatory Bowel Disease: The Gut in Disharmony Microbiome Rapozo DCM et al Therefore, it is likely that a better understanding of the role of different food components in intestinal homeostasis and the resident microbiota will be essential for unravelling the complex molecular basis of the epigenetic, genetic and environment interactions underlying IBD pathogenesis as well as for offering dietary interventions with minimal side effects. World J Gastroenterol , 23 (12), 2124-2140 2017 Mar 28
Jul 2016 The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions Microbiome Vindigni SM et al We discuss the tripartite pathophysiological circuit of inflammatory bowel disease (IBD), involving the intestinal microbiota, barrier function, and immune system. Dysfunction in each of these physiological components (dysbiosis, leaky gut, and inflammation) contributes in a mutually interdependent manner to IBD onset and exacerbation. Genetic and environmental risk factors lead to disruption of gut homeostasis: genetic risks predominantly affect the immune system, environmental risks predominantly affect the microbiota, and both affect barrier function. Therap Adv Gastroenterol . 2016 Jul;9(4):606-25. doi: 10.1177/1756283X16644242. Epub 2016 Apr 19.
Oct 2015 Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn’s Disease Microbiome Lewis JD et al Dietary therapy had independent and rapid effects on microbiota composition distinct from other stressor-induced changes and effectively reduced inflammation. These findings reveal that dysbiosis results from independent effects of inflammation, diet, and antibiotics and shed light on Crohn disease treatments. Cell Host Microbe , 18 (4), 489-500 2015 Oct 14
Jul 2012 Food and the Gut Microbiota in IBD: A Critical Connection Microbiome Albenberg LG et al Recent studies have demonstrated an association between the diet and the human microbiome. Because the development of a 'dysbiotic' microbiota is thought to be involved in the pathogenesis of IBD, diet is being investigated as an important etiologic factor. Curr Opin Gastroenterol , 28 (4), 314-20 Jul 2012

Nutritional Therapy for IBD

Improving the Care of Patients with Crohn’s Disease and Ulcerative Colitis through Diet