Ongoing Clinical Trials

The body of research examining therapeutic diets is growing. Many trials are still in progress, including several large multi-center trials (DIETOMICS-CD [CDED] and MELODY [IBD-AID]). The collection of ongoing clinical trials listed below has been cultivated from
Date Title Trial type Completed Diets Sponsor Summary Excerpt Trial
May 2019 Inflammatory Bowel Disease Tracker (IBD Tracker) (IBDTr) Observational Massachusetts General Hospital The goal for this study is to use non-invasive monitoring techniques to identify biomarkers that emerge, or change predictably, when a patient begins to relapse from remission to enter a period of disease - to find the earliest signs of an active flare. If the investigators identify a pattern of biomarkers that could alert a patient and their clinician to a flare as soon as it begins, it may be possible to intervene before symptoms present by changing medication and/or diet and lifestyle to lessen the severity of the disease flare. The biomarker fingerprint may also reveal new targets for therapeutics that could control IBD. Patient reported well being, 24 hour dietary recall, Smart Watch monitoring for activity, sleep, movement. Blood, stool, urine biomarkers measured throughout 12 month period, as well as biospecimens for microbiome and metabolite composition. Observational, prospective, 12 months, N=100

Nutritional Therapy for IBD

Improving the Care of Patients with Crohn’s Disease and Ulcerative Colitis through Diet