Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives

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Abstract

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Title
Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives
Type of Article
Primary Research
Diets studied
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Date
May 30, 2023
Author(s)
Raygoza Garay JA, Turpin W, Lee SH, et al
Publication
Gastroenterology
Citation

Raygoza Garay JA, Turpin W, Lee SH, et al. Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives. Gastroenterology. 2023;165(3):670-681. doi:10.1053/j.gastro.2023.05.032

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"The current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation."
"This study is the first to demonstrate that gut microbiome composition is associated with future onset of CD and suggests that gut microbiome is a contributor in the pathogenesis of CD."

Somebody in the kitch - view from the back while preparing healthy foods. Cutting board with various healthy foodsPink Milkshake and fruits on a white table and pink backgroundWoman stirring in a pot with vegetables.on the stove

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