Dietary manipulation of the gut microbiome in inflammatory bowel disease patients: Pilot study
Abstract
Olendzki, B., Bucci, V., Cawley, C., Maserati, R., McManus, M., Olednzki, E., Madziar, C., Chiang, D., Ward, D. V., Pellish, R., Foley, C., Bhattarai, S., McCormick, B. A., & Maldonado-Contreras, A. (2022). Dietary manipulation of the gut microbiome in inflammatory bowel disease patients: Pilot study. Gut Microbes, 14(1), 2046244. https://doi.org/10.1080/19490976.2022.2046244
Consumption of prebiotics, probiotics, and beneficial foods correlated with increased abundance of Clostridia and Bacteroides, commonly depleted in IBD cohorts. We further show that specific foods categorized as prebiotics or adverse foods are correlated to levels of cytokines in serum (i.e., GM-CSF, IL-6, IL-8, TNF-alpha) that play a central role in IBD pathogenesis.
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